Baeza and the venue are by themselves worth visiting
Charlène Boumendil (She/Her)
www.nature.com
HIV-1 capsid nuclear import at the nuclear pore complex is a bottleneck to resting T cell infection, but HIV-1 overcomes this by triggering receptor-mediated signalling during cell–cell spread to driv...
🎉 Now online! The Annual Review of Biophysics is now online. The most read article is "The Expanding Histone Universe: Histone-Based DNA Organization in Noneukaryotic Organisms" by Villalta et. arevie.ws/3R2CANN
@sashiw.bsky.social @nucleosomepolice.bsky.social
Video
Exciting!
One week left to apply to join us in sunny Montpellier as a group leader!
Karim Majzoub
Annual Reviews
Charlène Boumendil (She/Her)
Charlène Boumendil (She/Her)
First day of my PhD in IGBMC, internal seminar. An old man is sitting on the stairs. The talk ends and the old man asks a simple question, yet the most important and smart one. I turned to my colleague next to me: « Who is he? » That was Pierre Chambon. Incredibly smart, always exactly on point.
Pablo Navarro
We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...
We are looking for a new group leader to join the IGH (Montpellier, France). I can’t wait to meet my future colleague! Apply :-) More infos here: igh.cnrs.fr/join-igh-as-...
Kudos to @nadinelaguette.bsky.social team and all co-authors on this nice paper where our lab had a modest contribution! @viroscope.bsky.social 🔥
Although cohesin-sensitive, long-range enhancer activation is equivalent in nature to proximal activation. Cooperativity can arise from different levels of activation inputs operating on a non-linear response function. @eliasfriman.bsky.social @uoe-igc.bsky.social
www.biorxiv.org/content/10.6...
Out now in Science! Our study challenges long-standing assumptions about transcription factor specificity in eukaryotes. Novel single-molecule measurements of TF behavior in living cells reveal an independence of locus-specific binding from DNA sequence recognition.🧵
www.science.org/doi/10.1126/...
Charlène Boumendil (She/Her)
The Institute of Human Genetics invites applications for a Principal Investigator position in its main research areas. Read more...
(1/n) Super excited to share that our preprint is out today in @natsmb.nature.com with a new name "Integrated MINFLUX tracking reveals two distinct chromatin dynamics classes across cell types" and more than 2x more data:
www.nature.com/articles/s41...
See also MIT News news.mit.edu/2026/how-chr...
#RIP Pierre Chambon (1931-2026)
1963 PARP
1970 RNA Pol II
1975 Nucleosome
1977 Split genes
1980 Promoter
1983 enhancer
1986 Nuclear receptor
Vila, Messaoud-Nacer, Taffoni, @nadinelaguette.bsky.social et al show that DNA-PKcs, a major DNA damage response actor, interacts w/ cyclic dinucleotides through its kinase domain, ensuring CDN-associated signal termination, while CDNs inhibit DNA-PKcs catalytic activity rupress.org/jem/article/...
The list of speakers is very nice, mixing the two fields in synergy. Many abstracts will be selected for oral presentation.
How intrinsically disordered regions (IDRs) shape chromatin binding and nuclear organization of transcription factors (TFs) remains unclear. We used proximity-assisted photoactivation (PAPA), a single...
(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
Anders Sejr Hansen
Epigenetics means different things for different people. In this workshop we will discuss two major views anchored on transcriptional memory: chromatin vs networks.
Come and share with us our excitement for the topic and the magnificent place, the Andalusian Baeza.
urldefense.com/v3/__https:/...
Pablo Navarro
urldefense.com
The idea that cells remember past states to prepare their future endeavors has split into two parallel languages that rarely converse. On one side, chromatin epigenetics defines inheritance through th...
