Kudos to @nadinelaguette.bsky.social team and all co-authors on this nice paper where our lab had a modest contribution! @viroscope.bsky.social 🔥
Karim Majzoub
Vila, Messaoud-Nacer, Taffoni, @nadinelaguette.bsky.social et al show that DNA-PKcs, a major DNA damage response actor, interacts w/ cyclic dinucleotides through its kinase domain, ensuring CDN-associated signal termination, while CDNs inhibit DNA-PKcs catalytic activity rupress.org/jem/article/...
