I’m beyond happy to share that the preprint summarising my PhD research is now online on bioRxiv! 🚀
I am very grateful to my supervisors, Karen J Liu and Andrea Serio, all the coauthors and members of both teams who have made this work possible.
New pre-print on human neural crest organoids for studying developmental changes in diseases such as neuroblastoma. Heroic work from @carmenmorenogon.bsky.social bridging Liu/Serio labs @andreaserio.bsky.social with protocols from @tsakiridis.bsky.social.
www.biorxiv.org/content/10.6...
With new regulations taking effect, the question of which models best capture human disease is becoming increasingly urgent. In our April Editorial, we discuss why in vivo disease models remain essential, and our editors outline what in vitro systems can and cannot achieve.
doi.org/10.1242/dmm....
'Here, we describe a novel bioengineered pipeline to derive human pluripotent stem cell (hPSC)-derived neuroepithelial organoids, “neurocrestoids” featuring physiologically-relevant tissue architecture.'
#Preprint, Carmen Moreno-Gonzalez @karenjliu.bsky.social et al
www.biorxiv.org
Carmen Moreno Gonzalez
Karen J Liu
Looking forward to an exciting programme this Monday on Developmental Origins of Paediatric Cancers, sponsored by CCLG at the Crick. @tsakiridis.bsky.social www.cclg.org.uk/information-...
Fully funded PhD post, UK/Home student, starting 01/06/26. Interested in working at the interface of dev bio, biophysics and cell biology? Great collaboration with Amy Beedle and @leonerossetti.bsky.social Informal enquiries welcome. Deadline 15/03 #neuralcrest
www.kcl.ac.uk/study-legacy...
www.biorxiv.org
New pre-print on human neural crest organoids for studying developmental changes in diseases such as neuroblastoma. Heroic work from @carmenmorenogon.bsky.social bridging Liu/Serio labs @andreaserio.bsky.social with protocols from @tsakiridis.bsky.social.
www.biorxiv.org/content/10.6...
DMM Journal
Thiago Carvalho
A one-day event showcasing the latest cutting-edge research on the modelling, biology and treatment of paediatric cancers in the context of their developmental origins.
Last couple spots remaining for the Craniofacial GRC in sunny CA! Looks to be a full house, with a great set of up-and-coming #craniofacial biologists spanning evo/devo, genetics, multiomics all the way to stem cells, engineering and repair. @brugmannlab.bsky.social www.grc.org/craniofacial...
Think about craniofacial biology in sunny California😎! Don't forget to submit an abstract for the 2026 GRC Craniofacial. Many talk slots available from abstract selections. Deadline for talk abstracts 14 Dec, coming soon.... ☠️🐭🐟🐸🧬 #craniofacial #genetics #neuralcrest www.grc.org/craniofacial...
'We primarily do comparative analysis using human stem cells/organoids and genetically modified mouse models, with some minor use of frog models. We use this approach because, for developmental anomalies, it is impossible to assess true function without in vivo models'
@karenjliu.bsky.social
Abstract deadline looming! Coming join us in June for a great meeting on developmental origins of paediatric cancers, including neuroblastoma organised by @tsakiridis.bsky.social and friends @childrenwithcancer.bsky.social #neuralcrest www.crick.ac.uk/whats-on/dev...
The 2026 Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration will be held in Ventura, California. Apply today to reserve your spot.
www.grc.org
The 2026 Gordon Research Conference on Craniofacial Morphogenesis and Tissue Regeneration will be held in Ventura, California. Apply today to reserve your spot.
Summary: The call to arms for alternatives to model organisms of disease will fail without ongoing integration with – and validation against – complex animal models and support from the animal modelli...
