Join us as we discuss the latest immunology research, policy, and news with field experts. Brought to you by @stemcell.com.
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Immunology Podcast
New research published in Cell Press by @bcchresearch.bsky.social investigator Dr. Megan Levings and her team shows how using a standard approach to tracking immune cells is needed for both scientific research and the clinic.
Abstract: https://bit.ly/43jAyfb
News: https://bit.ly/4v88jvv
Introducing next week's guest!
Dr. Shabaana Khader (@khadershabaana.bsky.social) from the University of Chicago is an internationally recognized expert on #tuberculosis, its pathogenesis, and the microbiological and immunological aspects of TB infection.
Her latest work: https://bit.ly/4k7NLPD
Online now: A longitudinal atlas of human psoriatic skin reveals the mechanisms of anti-IL-23 therapy in disrupting the type 17 inflammatory circuit
A comprehensive pan-cancer atlas has revealed how diverse tumor-associated #macrophage subtypes promote tumor growth, immune suppression, and metastasis through interactions within the tumor microenvironment.
📖 Study: https://go.nature.com/4nYUHk6
🔊 Discussion: https://bit.ly/4o7wbx9
Be sure to catch next week's episode featuring Dr. Samuel Nobs from @irbbellinzona.bsky.social!
His research interests focus on the interplay between the microbiome and the lung immune system, in health and during disease.
🥼 Check out his research: https://go.nature.com/4a8YZzr
Tune into this week's episode with Dr. Samuel Nobs at @irbbellinzona.bsky.social!
He talks about how microbes in the lungs and gut may shape respiratory immunity and influence susceptibility to infections and chronic #LungDiseases. 🫁
🎧 Listen now: https://bit.ly/4uPWWZI
Dr. Ivan Zanoni, Kautilya Jena and Pengxiang Qu have shown that targeting antifungal immune receptors with a mannan-based adjuvant boosts the strength, durability, and variant coverage of #mRNAVaccine responses.
📑: https://go.nature.com/4uGnuME
🎧: https://bit.ly/4o7wbx9
New work from researchers at Keio University has shown that dietary #soy shapes the gut #microbiome to boost IgA-mediated immunity and enhance protection against intestinal infection in early life.
1️⃣ Read the study: https://bit.ly/4fPHkAz
2️⃣ Listen to the discussion: https://bit.ly/4o7wbx9
In a new study from the lab of Dr. Francis Jiggins at @geneticscam.bsky.social, researchers show that wild rabbits rapidly evolved resistance to #MyxomaVirus through changes in highly diverse MHC immune genes. 🐇
1️⃣ Study: https://bit.ly/4dhg1wc
2️⃣ Discussion: https://bit.ly/4o7wbx9
Gastrointestinal tuft cells: Recent insights and next questions | Science Immunology www.science.org/doi/10.1126/... 🧪
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Patients with psoriasis show a durable clinical response to the anti-IL-23 biologic, risankizumab, even after treatment cessation. Here, Jiang et al. generate a longitudinal single-cell and spatial transcriptomics atlas of patients pre- and post-treatment. They reveal reduced CD8+ tissue-resident memory T cell expansion, diminished inflammatory dendritic cells, and decreased APOE+/IL34+ fibroblasts associated with lasting amelioration of psoriatic inflammation.
