💬 Editorial: Statin guidelines and patient preferences for #ASCVD prevention often misalign, supporting the need for clearer risk communication and shared decision-making in clinical practice.
ja.ma/4eBIEX0
One-year follow-up of the RESiLIENT trial of smartphone CBT is out (n=3,280): CBT skills reduced major depression onset risk by 37–48%. But depression waxes and wanes. For the total burden of depression, behavioral activation + cognitive restructuring was the most effective. doi.org/10.1192/bjp....
doi.org
JAMA Internal Medicine
Dr. Eric Cadesky MD
After 40 years of working as psychiatrist and researcher, I cannot answer this question.
But that is how education goes. We don’t have as many RCTs of educational methods, do we?
📱 Could a smartphone app keep depression away — for nearly a year? A 3,280-person RCT says yes. CBT skills like behavioral activation & insomnia therapy cut the risk of major depression by up to 48% at 50 weeks. Prevention at scale is here. 🧵https://doi.org/10.1192/bjp.2026.10630
It appears that regulatory agencies are pretty ignorant of predictive/diagnostic modeling. A very similar thing happened with the Japanese PMDA.
