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3/3 Also exciting to see a complementary study from @angelifriedmann.bsky.social @veraskafar.bsky.social & colleagues published in Nature Cell Biol today. Together, our studies highlight a role for vitamin B2 metabolism and FAD in regulating FSP1 and ferroptosis. www.nature.com/articles/s41...
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After performing a focused CRISPR–Cas9 screen, Skafar et al. identify riboflavin (vitamin B2) as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in c...
www.nature.com
Riboflavin metabolism shapes FSP1-driven ferroptosis resistance - Nature Cell Biology
James Olzmann