By uncovering the origins of a group of rare immune cells called Thetis cells, #GilliamFellow Yoselin Paucar Iza & #FreemanHrabowski Scholar @chrysothemisbrown.bsky.social are unlocking these cells' potential to help treat — or even prevent — food allergies & autoimmune diseases: bit.ly/4cnQpii.
This complements a recent study in @cp-immunity.bsky.social on Runx regulation of RORγt across TC and LTi development
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
We are hiring! The Brown Lab is looking for a computational biologist to join our team.
If you enjoy working with single-cell and spatial genomics data and want to study how immune cells develop and function, we’d love to hear from you!
Apply here:
hhmi.wd1.myworkdayjobs.com/External/job...
Congrats to Ichiro Taniuchi's lab! Happy to have been part of this study with Yoselin Paucar Iza showing that Runx–CBFβ complexes are essential for the development of tolerogenic Thetis cells. Overexpression of Runx enhances TC IV and pTreg differentiation.
www.nature.com/articles/s41...
HHMI
Chrysothemis Brown
Chrysothemis Brown
Chrysothemis Brown
Beyond their well-established roles in type 3 immunity, RORγt+ innate immune cells are also essential for secondary lymphoid organ (SLO) formation and…
Primary Work Address: 1275 York Avenue, New York, NY, 10021 Current HHMI Employees, click here to apply via your Workday account. About the Lab The Brown Laboratory studies how the tissue microenviron...
Taniuchi and Brown and colleagues report that the Runx–CBFβ transcription factor complex plays a crucial role in the development of intestinal RORγt+ antigen-presenting cells, which are required to pr...
