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Jane Coffin Childs Fellow Dr. Michelle Fry studies perhaps the most iconic organelle of the cell, the mitochondria. Almost everyone knows that mitochondria are the powerhouse of the cell, but few know they are essential for other functions like respiration and ... @myfry.bsky.social 1/
Meet Friederike Benning, PhD, the newest Jim and Virginia Stowers Fellow! Her research dives into the complexity of energy generation in evolution to reveal how bacteria build membranes to survive in extreme environments. 🦠 Learn more: bit.ly/3SCZQiM
youtu.be/uM0wKYb1kus?...
JCC Featured Fellow Dr. Michelle Fry studies the structure of mitochondria – organelles that play important roles in cellular metabolism and signaling pathways. Fry uses the powerful technique cryoET to study mitochondrial shape right in their native environment in cells. @myfry.bsky.social 1/
Out in print! Using ancestral sequence reconstruction 🦖, in vivo characterization, and 🔬 analysis, we identified key residues in the mitochondrial protein #Mic60 that affect #respiration in #yeast. Since the preprint, we added some cool findings. 🧵⬇️ onlinelibrary.wiley.com/doi/10.1002/...
#AsgardArchaea team, led by @archaeal.bsky.social fr @texasscience.bsky.social — sequencing the DNA collected fr mouth of Rio de la Plata to the continental shelf of Uruguay to detect Asgards, a group of single-celled organisms & our closest microbial relatives on the tree of life. bit.ly/3MdniTH
1mo
May 15, 2025
I’m thrilled to share that I will join @stowersinstitute.bsky.social this fall to explore the evolution and design of bioenergetic membranes in bacteria.
It has been coming a long way... happy to share our latest work with you: www.biorxiv.org/content/10.1... Here, we show the importance of septal fortification by the Class A Penicillin Binding Protein, PBP1b, in E. coli and provide a molecular mechanism for this function. (1/12).
6mo
Congrats Chen and colleagues (with shoutout to @myfry.bsky.social for connecting our labs)! JCI - SARM1 loss protects retinal ganglion cells in a mouse model of Autosomal Dominant Optic Atrophy www.jci.org/articles/vie...
1mo
Jun 23, 2025
7mo
A new #preLight has appeared! ✨🔔 Barbora highlights a preprinted study from the Chao Lab (@lukechao.bsky.social) in which the structure-function relationship at the site of cellular respiration is under review. 👀 Check it out! ⬇️ prelights.biologists.com/highlights/a...
May 16, 2025
Apr 3, 2025
May 10, 2025
Mar 11, 2025
Stowers Institute
Video
Jane Coffin Childs Fund for Medical Research
Jane Coffin Childs Fund for Medical Research
Brett Baker
YouTube video by Schmidt Ocean
youtu.be
Searching for the Asgards | 4K ROV Highlights
Schmidt Ocean Institute
Freddy Benning
Freddy Benning
Video
In eukaryotes, cellular respiration takes place in the cristae of mitochondria. The mitochondrial inner membrane protein Mic60, a core component of the mitochondrial contact site and cristae organizi...
Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast
onlinelibrary.wiley.com
www.jci.org
JCI - SARM1 loss protects retinal ganglion cells in a mouse model of Autosomal Dominant Optic Atrophy
Andrea Vettiger
Luke Chao
A multi-protein system called the divisome promotes bacterial division. This apparatus synthesizes the peptidoglycan (PG) cell wall layer that forms the daughter cell poles and protects them from osmo...
www.biorxiv.org
The aPBP-type cell wall synthase PBP1b plays a specialized role in fortifying the Escherichia coli division site against osmotic rupture
preLights
In this preprint the structure-function relationship at the site of cellular respiration is under review.
Ancestral sequence reconstruction of the Mic60 Mitofilin domain reveals residues supporting respiration in yeast - preLights
prelights.biologists.com
Meet Friederike Benning, PhD, the newest Jim and Virginia Stowers Fellow! Her research dives into the complexity of energy generation in evolution to reveal how bacteria build membranes to survive in extreme environments. 🦠 Learn more: bit.ly/3SCZQiM
May 15, 2025
Video
Stowers Institute