Happy to reveal our latest work, Microbe-Independent Deep Assembly and Screening (MIDAS), a method for engineering proteins >10x more cheaply and quickly than before.
MIDAS addresses the slowest step in protein engineering — construction and expression of variants — by skipping cloning entirely
Michael Lin, MD PhD
Faculty Fellow Michael Lin introduces MIDAS, a new method that builds and tests thousands of protein variants in days instead of weeks - delivering an order-of-magnitude improvement in speed and cost and advancing how proteins are engineered and studied:
link.springer.com
Traditional methods for engineering and sequence-fitness analysis of proteins in mammalian cells are limited by the time, cost, and labor associated with plasmid cloning and preparation. Here we…