So excited to see this fabulous work by stellar MD-PhD student Briana Macedo now out as a preprint. Briana reports some of the strongest results I've ever seen -- very strong (25% variance, out-of-sample) associations between the childhood environment and white matter. Thread below!
Optimizing functional connectivity scanning conditions for predicting autistic traits ft. @coreyhorien.bsky.social & @ted-satterthwaite.bsky.social (Psych) www.nature.com/articles/s44...
Nice article on our recent Nature Mental Health paper: www.medscape.com/viewarticle/...
What matters most for childhood brain organization?
We analyzed 649 variables.
The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers.
Even brain-IQ associations were better explained by SES.
In Science today: www.science.org/doi/10.1126/...
🧠‼️ Socioeconomic variables show the strongest associations with the brain out of 649 measures—surpassing cognition and mental health. Grateful for the chance to write a perspective with @ted-satterthwaite.bsky.social about @smarek0502.bsky.social and team's important findings! tinyurl.com/bdhk6bc8
Thanks @ariellekeller.bsky.social !
And yes, please check out the amazing perspective by @lucindasisk.bsky.social and @ted-satterthwaite.bsky.social!
Very excited about this project, led by @zachladwig.bsky.social
We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches.
Full🧵 coming soon!
Sypres.io continuously tracks and evaluates psychedelic research, offering an up-to date view of study findings, design, and limitations.
www.medscape.com
Incredible work!!!!
Postdoc opening w/ a great team inc close collab Dan Wolf! fMRI + computational modeling in NIH-funded clinical high risk for psychosis study. U. Maryland in collaboration with UPenn + Mt. Sinai. Full posting here: umb.taleo.net/careersection/jobdetail.ftl?job=260000DJ
Congrats Corey!!!!!
Socioeconomic factors top the list of influences on children’s brain structure and function
What matters most for childhood brain organization?
We analyzed 649 variables.
The answer: Socioeconomics (SES); with brain patterns pointing at sleep & stress as drivers.
Even brain-IQ associations were better explained by SES.
In Science today: www.science.org/doi/10.1126/...
Ted Satterthwaite
Ted Satterthwaite
Ted Satterthwaite
Parker Singleton
Ted Satterthwaite
Very excited about this project, led by @zachladwig.bsky.social
We show that an individual’s lateral prefrontal cortex has reliable and highly detailed network organization missed in past group approaches.
Full🧵 coming soon!
Lucinda Sisk
Scott Marek
Ladwig et al. use precision fMRI methods to show that the lateral prefrontal cortex of individuals features a mosaic of functionally dissociable network patches rather than a single, broad, and functionally flexible region, as suggested by group-averaged data.dlvr.it
Ladwig et al. use precision fMRI methods to show that the lateral prefrontal cortex of individuals features a mosaic of functionally dissociable network patches rather than a single, broad, and functionally flexible region, as suggested by group-averaged data.
The evidence is clear: socioeconomic conditions play an *enormous* role in brain development
Amazing work by @smarek0502.bsky.social &co
doi.org/10.1126/science.aee6213
+perspective by @lucindasisk.bsky.social & @ted-satterthwaite.bsky.social
doi.org/10.1126/science.aei3393
#neuroskyence #PsychSky
Neuron
Neuron
Little work has focused on the optimal brain states to reveal brain–phenotype relationships. Here, using connectome-based predictive modeling, we interrogated four datasets to determine scanning conditions that boost prediction of clinically relevant phenotypes and assess generalizability.
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