The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes:
🖌️ Dozens more images with duplications or painting
🖨️ Hundreds of blots that all share the same background (behold slideshow below)
How can we learn tissue mechanics directly from cell patterns and images?
In our new preprint, we introduce VertAX, a differentiable vertex-model framework in JAX for simulating epithelia, inferring parameters, and designing target tissue behaviors.
shorturl.at/PUzT0
1/5
Video
A day in the life of a growing hiPSC spheroid expressing endogenously mStayGold-tagged histone 3.3 for #FluorescenceFriday and the #Snouty aficionados. 28 hours (and >50,000 exposures) later and they are still going! Home-brewed volume projection.
Reese Richardson
Turlier lab
Video
Our review article is now available in Annual Review of Condensed Matter Physics: “Full-Integer Topological Defects in Polar Active Matter.” @luizaangheluta.bsky.social @emmalaang.bsky.social doi.org/10.1146/annu...
We present a new mechanism for triggering the flocking transition in epithelia, involving extensile polar defects and domain walls. Very happy to share this work, done in great collaboration with the @luizaangheluta.bsky.social group.
preprint: arxiv.org/abs/2605.23339
Happy to share our new paper on collective cell dynamics. Great work from Yuan Shen @ijmonod.bsky.social !
Dynamic heterogeneity and hidden fluidity in dense epithelial tissues | Science Advances www.science.org/doi/10.1126/...
Searching for a new job?
We’re hiring a Postdoctoral Fellow for an exciting new research project on Hidradenitis Suppurativa.
Apply now and please pass this on to anyone who might be interested!
www.finn.no/job/ad/44835...
Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de
🚀 KiloHz two photon live imaging #MultiphotonMicroscopy @laboptbio.bsky.social
Two-photon light-sheet live imaging at kilohertz frame rate using birefringence-based pulse splitting
#LightSheetMicroscopy #Bioimaging #Photonics #Microscopy #Zebrafish
Article is available here: doi.org/10.1364/OPTI...
Torsten Wittmann
Video
Densely packed epithelial tissues appear mechanically arrested at tissue scale, but their cells move in subtle, coordinated ways.
www.science.org
Project titleNavigating the Tunnel: Keratinocyte Dynamics & Therapeutic Targeting of IL-17 in Hidradenitis Suppurativa Position summaryWe seek a motivated
Microfluidic pumping with active nematics! Self-organized and self-sustained. No external pumps.
@pnas.org @ub.edu
www.pnas.org/doi/10.1073/...
#ActiveMatter #Microfluidics #SoftMatter
Benoit Ladoux
Brugues Lab
Microfluidics involves the manipulation of flows at the microscale, typically requiring
external power sources to generate pressure gradients. Alte...