Inlay

Thrilled to announce a new @natcomms.nature.com paper led by Alastair Stewart and team @victorchang.edu.au with contributions from @mcdevittlab.bsky.social Using #cryoEM we discovered unique features of the #Pseudomonas aeruginosa ATP synthase including an unexpected role for #zinc in the complex 🦠🔬

Antimicrobial Resistance #AMR is a term most people have never heard of before yet it's a global health crisis Our charity, #theAMRnarrative has created a 90-second explainer video to help you grasp the basics youtu.be/S_0XQ5LhA6o?... #AntibioticResistance #AntimicrobialResistance #GlobalHealth

🚀 PhD Opportunity on Infectious Diseases and #AMR! 🧬🔬 Are you passionate about understanding how #bacteria acquire essential #biometals and cause disease? We have fully funded joint PhD project (@thedohertyinst.bsky.social) with Prof. Trevor Moraes (@utoronto.ca). To find out more: bit.ly/4pMfmI4

🚀 Proud McDevitt Team #student achievements! 🌟 🎉 Salma smashed the #UniMelb #3MT 🏆 🎉 Abigail nailed the #Doherty Symposium Poster Award 🏅 🔥 These two are unstoppable! #PhDlife #Research #AcademicTwitter

Congratulations to @camcdevitt.bsky.social @ellacasale.bsky.social and @blisscunningham.bsky.social for progressing in the CSIRO ON Innovation program to the ON Core stage. Great insights, advice and support on how to bring new #biomedical #AMR #technology to patients. wp.csiro.au/oncore/

The costs of #antimicrobial resistance 🦠 continue to rise 📈. The Center for Global Development reports that by 2050 #AMR could shrink the global economy by US$1.7T. Improving treatments and funding development of new antimicrobials 💊 could save millions of lives and billions in healthcare costs.

Doherty Institute secures $12.9M NHMRC Ideas Grants for 9 projects tackling antimicrobial resistance, TB, HIV, cancer immunology & immune biology—advancing new ways to fight infections & immune-related diseases. 🔗 https://bit.ly/4aJ6gas

Klebsiella pneumoniae is a Gram-negative opportunistic pathogen and a World Health Organization (WHO) priority organism, owing to rising rates of multidrug resistance and the increasing burden of infections in both community and healthcare settings. These challenges, together with the lack of an effective vaccine, highlight an urgent need to identify new therapeutic targets for the treatment of K. pneumoniae infections. Zinc is an essential first-row transition metal ion required by all forms of life. In bacteria, zinc has critical roles in cellular physiology and virulence. This PhD project will employ state-of-the-art molecular, structural, and elemental analytical techniques to characterise newly identified systems involved in K. pneumoniae zinc acquisition and resistance. The project will examine how these systems contribute to evasion of host innate immune responses and antimicrobial resistance. Insights gained from this work will provide a strong foundation for the development of novel therapeutics targeting bacterial metal homeostasis pathways.

Congratulations 👏 to Matt Giles for representing @mcdevittlab.bsky.social and the Moraes group at the CanBIC-9 conference. A great presentation sharing his recent work on the #zinc uptake pathways in the #AMR bacterial pathogen 🦠 #Klebsiella pneumoniae.

Excited to announce a funded #PhD project with my amazing colleagues Jeff Harmer and Evelyne Deplazes (Uni of Queensland). This collaborative project uses #biochemistry 🧪, advanced spectroscopy, and computational approaches 🖥️ to study a #zinc export system in a priority pathogen 🦠. Find out more at:

Hello world 🌏 The @mcdevittlab.bsky.social team 🧑‍🔬👩‍🔬👨‍🔬 and I will be posting updates here and on LinkedIn going forward as we depart Twitter/X. We look forward to sharing our exciting 🧪🔬🦠🧫 work on #biometals, #infection, #bacteriology, #AMR, and #antibiotic development with this community.