Check out our new work @natcomms.nature.com! @mayorlab.bsky.social discovered that cells perform durotaxis even without focal adhesions. How? Well, we found that they actually follow friction gradients — a new mode of directed cell migration that we call frictiotaxis!
www.nature.com/articles/s41...
Cells typically migrate toward stiffer substrates via durotaxis, relying on focal adhesions. Here, the authors show that confined cells can migrate up friction gradients without focal adhesions, revea...