Traceable traceless delivery tags: The tasty title of our new paper in Helv. Chim. Acta refers to the dual function of asparagusic acid, thiol-mediated uptake and Golgi tracking, at best inner membrane leaflet, cis Golgi lumen and trafficking from threre.
onlinelibrary.wiley.com/doi/10.1002/...
Glad to see our paper published in @greenchemistry.rsc.org
pubs.rsc.org/en/content/a...
Excited to share Sophia’s and Luca’s work assessing the #synthesis #structure and #reactivity of a homologous series of #AlkaliMetal #silyl complexes! Just out in #Organometallics @pubs.acs.org
@unibe.ch
pubs.acs.org/doi/abs/10.1...
Enabling technologies are perceived as inherently sustainable, due to the replacement of stoichiometric oxidants and reductants with traceless redox mediators such as photons or electrons. However, th...pubs.rsc.org
Long Covid research takes some major steps forward:
The fiddler-crab-type boranes take on another notoriously difficult transformation: the direct reduction of esters to ethers!🦀
We are thrilled to share that our latest research has just been published as a VIP paper in @angewandtechemie.bsky.social!🎉
Check it out:
doi.org/10.1002/anie...
Gabriele Laudadio
The Matile Group
Eva Hevia
I would classify myself generally as skeptical of review articles, but (with obvious bias) I am hopeful that this one is unusual, in a good way! We tried to put in one place a bunch of important ideas that have been driving the lab's thinking recently.
pubs.acs.org/doi/10.1021/...
Check out our new tutorial review in Green Chemistry !!
👉👉 shorturl.at/KRblD
Rethinking photocatalysis: TADF compounds challenge metal-based complexes as efficient, sustainable alternatives—even in energy transfer.
@unipd.bsky.social
Happy to share our work on the use of bench-stable trivalent iminyl phosphines enabling visible-light SET generation of phosphoryl radicals, a novel way to forge P-N bonds within elusive azetidine scaffolds !
@angewandtechemie.bsky.social @unipd.bsky.social
🚩 shorturl.at/0Jrd1 🚩
C-Glycosyl bicyclo[1.1.1]pentanes (BCPs) are saturated analogues of aryl C-glycosides; however, the available methods for their preparation remain limited in scope and generality. Herein, we develop a...
Electrochemistry to the next sustainable level: In our first work of the year, we present a general water/propylene carbonate mixture to carry out anodic reactions.
Check it out!
t.co/vKTiLTF0ga
Recent advances have made possible the replacement of individual atoms within a molecular skeleton while preserving the integrity of the surrounding framework. These skeletal editing reactions are emerging as powerful tools for molecular optimization, as they directly mirror tactics central to structure–activity-relationship studies and therefore have the potential to accelerate progress in discovery chemistry settings. This review introduces a comprehensive framework for categorizing atom replacement reactions in aromatic systems, while also delineating strategies that enable these transformations. Important heuristics related to shape-conservation are discussed, including notions of skeletal rotation, introduction of vestigial substituents, and retrosynthetic simplicity. Examples of reactions which obey these principles are analyzed, focusing first on C-to-N replacement in aromatic systems (“benzene to pyridine” and related reactions) before moving to other classes of aromatic and aliphatic replacement reactions.
Recently, TADF (thermally activated delayed fluorescence) compounds have expanded their role beyond materials chemistry, enriching the field of photocatalysis and offering a cost-effective and environ...
doi.org
Photochemically generated phosphoryl radicals from iminyl phosphines enable strain-release addition to azabicyclobutanes, providing access to elusive N-phosphoryl azetidines. Combined experimental, c....
