📣 New preprint: Mechanochemical feedback, tissue geometry & rigid-body dynamics initiate rotational migration in Drosophila via spontaneous chiral symmetry breaking. A mechanism generalizable to closed epithelia.
@sreejithsanthosh.bsky.social
biorxiv.org/content/10.1...
Video
Mattia Serra
Here’s my recent work on biomolecular condensates. In this paper, we address how small molecules shift the phase equilibria of condensates. We describe how underlying protein–solute interactions determine the observed shifts and develop a theoretical framework using standard thermodynamic theory.
In this issue: A parasite drives movement in infected red blood cells, electric charges can accelerate without emitting radiation, and stratospheric methane loss. In PNAS: https://ow.ly/c6bK50Yi61j
Here’s another condensate paper from the lab. We revisit biomolecular condensation—phase separation in protein suspensions—through the lens of critical phenomena. Kaarthik did excellent work characterizing mechanical properties and comparing their scaling behavior to the 3D Ising universality class.
Takumi Matsuzawa
Takumi Matsuzawa
Proceedings of the National Academy of Sciences
Happy to share our first preprints from work originating at Cornell!
Takumi's paper describes how small molecules shift phase equilibria of condensates by focusing on the dilute-phase response. It shows how metabolites may tune stability and material properties.
www.biorxiv.org/content/10.6...
Our second Cornell-era preprint is also out!
Kaarthik's paper discusses the gap between cellular and in vitro condensates. In cells, condensates are low-contrast (small partition coefficients), enabling a wide range of responses.
Congrats, Kaarthik and the team!
www.biorxiv.org/content/10.6...
Laboratory of Soft and Living Materials @SoftLiv_Cornell
Laboratory of Soft and Living Materials @SoftLiv_Cornell
