Therapeutic complement inhibitors, which target complement pathway components, could revolutionize treatment for a broad range of kidney diseases. Read this Review of targeted treatments for glomerular diseases. Open Access
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IPNA Pediatric Nephrology
Idiopathic nephrotic syndrome (NS) is the most common glomerular disease in children. Read this Systematic Review /Meta-analysis of steroid-induced adrenal insufficiency in children w/NS. Open Access
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Primary hyperoxaluria type 2 is a rare genetic disorder of oxalate due to a defect in the glyoxalate reductase/ hydroxypyruvate reductase enzyme. Read this Original Article on characteristics & outcomes in a pediatric population in Pakistan.
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Hemoadsorption devices are a major advancement in extracorporeal organ support therapies. Read this Educational Review of technicalities, current evidence, & clinical indications of hemoadsorption in critically ill children. Free access this month.
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Corticosteroids are the cornerstone of therapy for steroid-sensitive nephrotic syndrome, yet the best dosing strategy remains uncertain. Read this Systematic Review /Meta-analysis of single-dose vs. multi-dose steroid therapy in pediatric NS. Open Access
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Children w/chronic liver disease are at increased risk of AKI, which could be non-hepatorenal syndrome AKI (non-HRS-AKI) or hepatorenal syndrome AKI (HRS-AKI). Read this Review of terlipressin in pediatric HRS-AKI. Open Access
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Anti-CD20 monoclonal antibodies (mAbs), which act as B-cell–depleting therapies, are important treatments for a range of pediatric kidney diseases. Read this Educ Review of infection prophylaxis following mAbs in childhood kidney diseases. Open Access
link.springer.com/article/10.1...
Antenatal hydronephrosis (HN) is the most common congenital urinary tract abnormality, but mgmt is controversial. Read this Original Article on safely limiting antibiotic prophylaxis & invasive testing in asymptomatic children w/antenatally detected HN.
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AI is rapidly transforming many areas of medicine, & pediatric nephrology may be a field of particular relevance. Read this Review of AI in pediatric nephrology: current applications & emerging frameworks. Open Access
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Clinical significance of positive urine cultures in febrile infants w/negative dipsticks remains debated. Read this Original Article on urine cultures in low-risk febrile infants < 3 months old w/negative urine dipsticks. Open Access
link.springer.com/article/10.1...
