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www.biorxiv.org/content/10.1.... Our attempt to understand myopathy and exercise intolerance in PAH in greater detail.
Mar 29, 2025
Background: Pulmonary arterial hypertension (PAH) is a rare but debilitating condition that causes exercise intolerance and ultimately death. Skeletal muscle derangements contribute to depressed exerc...
Proteomic and Metabolomic Profiling Nominates Druggable Targets and Biomarkers for Pulmonary Arterial Hypertension-Associated Myopathy and Exercise Intolerance
www.biorxiv.org
www.atsjournals.org/doi/10.1164/...
What an amazing #AHA24 with a great team! Jenna wins the gold!
Nov 18, 2024
Dec 20, 2024
www.jci.org/articles/vie.... Our attempt to take in end-organ dysfunction with the liver as our focus in PAH/RV Failure. @jci.org @natrevgastrohep.nature.com @the-asci.org @mark-toshner.bsky.social
www.ahajournals.org/doi/10.1161/.... Our most recent work attacking RV failure! @mark-toshner.bsky.social @ahascience.bsky.social @ahajournals.bsky.social
www.jci.org/articles/vie.... Now out in @jci.org, estrogen exerts cardio protective effects via microtubule modulation!
Our latest attack on RV failure is out! www.ahajournals.org/doi/10.1161/...
I was so impressed by the beauty of the Duke campus!
13d
1mo
May 16, 2025
8mo
Dec 19, 2024
www.atsjournals.org
Ferroptosis Inhibition Combats Metabolic Derangements and Improves Cardiac Function in Pulmonary Artery Banded Pigs | American Journal of Respiratory and Critical Care Medicine | Articles in Press
BACKGROUND: Inflammation suppresses right ventricular (RV) function in pulmonary arterial hypertension (PAH). In particular, we showed GP130 (glycoprotein-130) signaling promotes pathological microtub...
www.ahajournals.org
Lactobacillus Restructures the Micro/Mycobiome to Combat Inflammation-Mediated Right Ventricular Dysfunction in Pulmonary Arterial Hypertension | Circulation: Heart Failure
www.jci.org
JCI - Pulmonary Arterial Hypertension Induces a Metabolic and Inflammatory Hepatopathy
BACKGROUND: Right ventricular (RV) dysfunction is a risk factor for death in multiple cardiovascular diseases, but RV-enhancing therapies are lacking. Inhibition of GP130 (glycoprotein-130) signaling ...
www.ahajournals.org
GP130 Antagonism Enhances Porcine RV Function | Circulation Research
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😁Congratulations to Stephen L. Archer, MD, recipient of the PC Robert F. Grover Award! @ats-pc.bsky.social This prestigious recognition honors outstanding contributions to pulmonary vascular disease research and innovation. @drstephenarcher.bsky.social Learn more: site.thoracic.org/assemblies/p...
1mo
It’s borderline criminal.
ATS Assemblies
Mar 8, 2025
George Takei