#Insulin resistance alters cortical inhibitory neurons and #microglia to exacerbate #Alzheimers knock-in mouse phenotypes
LaShae Nicholson, Si Jie Tang, Tejaswini Karra, Habiba Abouelatta, Stephen M. Strittmatter #obesity #diabetes
link.springer.com/article/10.1...
Tau extent outperforms tau load as a predictor of #neurodegeneration in #AlzheimersDisease
Arthur C. Macedo, Lydia Trudel, Seyyed Ali Hosseini...Pedro Rosa-Neto @mcgilluniversity.bsky.social
link.springer.com/article/10.1...
#Cholesterol metabolism in #neurodegenerative diseases: mechanisms and therapeutic advances
Dezhen Tu, Yuxiao Zheng, Pingping Ding, Miao Shen...Bin Wei & Hongyan Wang #microglia #astrocytes #oligodendrocytes
link.springer.com/article/10.1...
#Neurodegeneration as an #evolutionary trade-off: a biological constraint–aware #therapeutic perspective
Seung Hyun Kim, Min-Young Noh, Matthew C. Kiernan
link.springer.com/article/10.1...
In vivo profiling of #astrocyte secretome reveals brain-region specific regulatory networks in a mouse model of #amyloid pathology
Qiu Jiang, Jian-Ni Hu, Hao-Min Dong...Jie Liu & Yan-Jiang Wang #AlzheimersDisease
link.springer.com/article/10.1...
3’UTR regulation of #axon translation and
#OpticNerveRegeneration
Minjuan Bian, Emma L. Huie, Xin Xia...Jeffrey L. Goldberg @stanfordmedicine.bsky.social
link.springer.com/article/10.1...
RAN translation as a dominant pathogenic axis in #C9ORF72 -associated ALS and FTD models
Pegah Masrori & Defne Audrey Amado @pennmedicine.bsky.social #AmyotrophicLateralSclerosis #FrontotemporalDementia
link.springer.com/article/10.1...
Correction: Decoding distinctive features of plasma extracellular vesicles in amyotrophic lateral sclerosis
link.springer.com/article/10.1...
Temporal single-cell atlas of full-length #Huntington disease mouse model defines stage-specific signatures of #corticostriatal dysfunction
Ashley B. Robbins...Beverly L. Davidson @childrensphila.bsky.social #neurodegeneration #omics
link.springer.com/article/10.1...
Dual orexin receptor antagonism with lemborexant enhances #microglial clearance of β-#amyloid in mice
Ashish Sharma, Emiko Segawa, Xiaoying Chen...Erik S. Musiek @washumedicine.bsky.social #Sleep #AlzheimersDisease
link.springer.com/article/10.1...
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Molecular Neurodegeneration
Coordinated cell-to-cell communications is crucial for the proper functioning and maintenance of brain activities, and its disruption contributes to neurological disorders, including Alzheimer’s disea...
