Some good news during these difficult times. Please check out our new preprint. We built a new tool to probe the origins of high oocyte aneuploidy rates at advanced female reproductive ages. This NIH funded work was led by a fantastic postdoc in the lab, Jiyeon Leem. www.biorxiv.org/content/10.1...
Proud of the first Brazilian movie to win an Oscar! "I am still here".
Nice work from @takashiakeralab.bsky.social: Spindle checkpoint can secure additional cheating time for selfish expanded centromeres: Current Biology www.cell.com/current-biol...
📣Huge congrats to our postdoc, Takaya Totsuka, on his new paper @currentbiology.bsky.social 🎉 He found that Ca2+ oscillations regulate oocyte spindle rotation! 🐭The project started during his PhD with Prof. Miho Ohsugi.
Free link: authors.elsevier.com/c/1lUqk3QW8S...
I’m happy to announce that our preprint is out! 🧬🐭
We show that the mouse HSR selfish DNA kills embryos that do not inherit it through a toxin–antidote system, thereby increasing its transmission to the next generation. ⚡
Feedback is welcome!
@takashiakeralab.bsky.social
#SelfishDNA #meiosis4eva
Proper organelle regulation during mitosis is a must, but how do membrane-less condensates like PML bodies behave during cell division? In work led by Eric Aird, we found the balance of speckled proteins SP110 & SP100 to be the key. doi.org/10.1038/s415...
Female reproductive aging is accompanied by a dramatic rise in the incidence of egg aneuploidy. Premature loss of chromosome cohesion proteins and untimely separation of chromosomes is thought to unde...
Expanded centromere DNA repeats violate Mendel’s law of segregation by preferentially
segregating to the egg in animals and plants. Using oocytes collected from hybrid
mice, Walton et al. show that th...
🚨Our latest work on selfish centromeres is published @currentbiology.bsky.social 🐭🧬We found that the spindle checkpoint contributes to non-Mendelian segregation! Huge congrats to our lab manager, Zaak Walton, who led the project🎉
Free link:
authors.elsevier.com/a/1lQzN3QW8S...
New Akera's lab paper! Congrats @takashiakeralab.bsky.social and Eddie!
Duilio Silva
Duilio Silva
Harmit Singh Malik
Takashi Akera Lab
Jacob Corn
Binyam Mogessie ቢንያም ሞገሴ
We are hiring POSTDOC now!🚨please repost! Fully-funded 5-year position 👩🏻🔬👨🔬🧬Looking forward to your application!✉️
O BRASIL CONQUISTA SEU PRIMEIRO OSCAR
AINDA ESTOU AQUI VENCE COMO MELHOR FILME INTERNACIONAL
É NOSSO, É NOSSOOOOOOOOOOOOOOO
Takashi Akera Lab
authors.elsevier.com
www.nature.com
In general, the kinetochore position and the sister-chromatid cohesion site are spatially linked. Here, the authors find a meiosis-specific distal cohesion site decoupled from the kinetochore in Perom...
