First real post on the new blog!
If you follow human genetics, you've likely of "missing heritability". If you look at twins to estimate heritability, you get values much larger than what molecular genomic methods produce. IQ, for example, goes from 50-80% heritability to 10-15%. Which is right?
Be sure to read the Invited Commentary by Brian Charlesworth, "How is variation in fitness maintained?"
academic.oup.com/evolut/artic...
Kevin Bird
Evolution
Abstract. The existence of substantial additive genetic variance in fitness poses a long-standing question for evolutionary geneticists. A new theoretical
The SIRA Act is the latest effort by conservatives to halt all research interactions with China on the grounds that they pose an imminent threat to U.S. national security. https://scim.ag/4wYBXFu
For this month's GBE Highlight, SMBE Fellow Haoran Cai delves into Adey et al., who investigated the role of pervasive transcription in the human genome.
@haorancai.bsky.social
🔗 doi.org/10.1093/gbe/evag104
#genome #evolution #highlight
This article is the focus of this month's GBE Highlight, written by SMBE Fellow Haoran Cai.
@haorancai.bsky.social
“Dark” or “Junk”? Functional Roles of Pervasive Transcription in the Human Genome
🔗 doi.org/10.1093/gbe/evag104
www.science.org
Critics say bill would weaken U.S. science by cutting flows of ideas and talent
I assigned random gender/ethnicity labels to scientific abstracts from the literature and then asked Claude to do a thematic analysis. Claude identified a clinical versus computational split for female/male authors and a DEI focus for Black/URM authors. All in completely random data.
Exploring the Genotype-to-Phenotype Map Using Quantifiable Patterns in Metazoan Genomic and Morphological Data by Peterson et al.
Available now ahead of print!
www.journals.uchicago.edu/doi/10.1086/...
I'm presenting this study for the virtual meeting of @evolmtg.bsky.social on May 22 at 6:15 PM Eastern Time. Please come!
Why are leaves the shape that they are? What controls intraspecific, genetic variation in leaf shape?
New from my lab, in collaboration with many others, led by PhD student Amanda Peake: mapping the leaf shape polymorphism in Ipomoea hederacea.
Daohan "Rex" Jiang
Sasha Gusev
American Naturalist / ASN 🐌
New preprint alert! In this study, we tackled a long-debated question: is the genetic basis of convergent evolution predictable? Should we expect the same gene/loci contributing to convergent adaptation to a common selective pressure? Thread ahead 1/n www.biorxiv.org/content/10.6...