Evolutionary and Quantitative Genetics | Regulatory evolution | GP map | Complex trait | Theory
haorancai.github.io
Post-doc @UCLA EEB
Haoran Cai
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I assigned random gender/ethnicity labels to scientific abstracts from the literature and then asked Claude to do a thematic analysis. Claude identified a clinical versus computational split for female/male authors and a DEI focus for Black/URM authors. All in completely random data.
Sasha Gusev
The SIRA Act is the latest effort by conservatives to halt all research interactions with China on the grounds that they pose an imminent threat to U.S. national security. https://scim.ag/4wYBXFu
Science Magazine
Be sure to read the Invited Commentary by Brian Charlesworth, "How is variation in fitness maintained?"
academic.oup.com/evolut/artic...
Abstract. The existence of substantial additive genetic variance in fitness poses a long-standing question for evolutionary geneticists. A new theoretical
Exploring the Genotype-to-Phenotype Map Using Quantifiable Patterns in Metazoan Genomic and Morphological Data by Peterson et al.
Available now ahead of print!
www.journals.uchicago.edu/doi/10.1086/...
I'm presenting this study for the virtual meeting of @evolmtg.bsky.social on May 22 at 6:15 PM Eastern Time. Please come!
This article is the focus of this month's GBE Highlight, written by SMBE Fellow Haoran Cai.
@haorancai.bsky.social
“Dark” or “Junk”? Functional Roles of Pervasive Transcription in the Human Genome
🔗 doi.org/10.1093/gbe/evag104
First real post on the new blog!
If you follow human genetics, you've likely of "missing heritability". If you look at twins to estimate heritability, you get values much larger than what molecular genomic methods produce. IQ, for example, goes from 50-80% heritability to 10-15%. Which is right?
Why are leaves the shape that they are? What controls intraspecific, genetic variation in leaf shape?
New from my lab, in collaboration with many others, led by PhD student Amanda Peake: mapping the leaf shape polymorphism in Ipomoea hederacea.
Evolution
Daohan "Rex" Jiang
American Naturalist / ASN 🐌
Genome Biology and Evolution
For this month's GBE Highlight, SMBE Fellow Haoran Cai delves into Adey et al., who investigated the role of pervasive transcription in the human genome.
@haorancai.bsky.social
🔗 doi.org/10.1093/gbe/evag104
#genome #evolution #highlight
Critics say bill would weaken U.S. science by cutting flows of ideas and talent
