I’m excited to share that my PhD paper is officially out now in @bloodjournals.hematology.org
Check out our discovery of how mutant IDH1 but not IDH2 leads to a lineage-specific differentiation block via epigenetic repression of lineage programs!
📄 Paper link below: 👇
doi.org/10.1182/bloo...
#StandUpForScience👩🔬👨🔬📢Scientists at the Max Planck Institute for Molecular Genetics in Berlin, including our managing director, show solidarity with our colleagues in the US who are protesting against the attacks of the current US administration.
@standupforscience.bsky.social @maxplanck.de
Fantastic milestone from the global HCA community..
Some highlights in the Nature N&V by @itaiyanai.bsky.social, Simon Haas, Christoph Lippert & Helene Kretzmer www.nature.com/articles/d41...
Muzz Haniffa
Max Planck Institute for Molecular Genetics
🧵 NEW PAPER in @bloodjournal.bsky.social!
Why do IDH1 mutations almost exclusively drive myeloid #leukemia, while IDH2 mutations occur in both myeloid AND lymphoid cancers? 🤔 #AML #Epigenetics
Despite sharing the same biochemical mechanism, they are NOT equivalent. Here's what we found 👇
