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Apply now to Amgen’s postbacc program!
2mo
Ryan Potts - real
SCAM ALERT. This is a fake conference that ripped off my and other people’s names to trick people into registering. There is no such conference that I or the others shown were invited or agreed to. We are working to try to get this fraud taken down from the web. chemsymposia.com
Check out how the Amgen Induced Proximity team repurpose lysosomal membrane proteins for targeted protein relocalization and degradation using LYMTAC molecules. Now published in @NatureComms. Congrats to @dnalawansha0509.bsky.social and team! #mycompany www.nature.com/articles/s41...
www.science.org/doi/10.1126/...
Apr 11, 2025
10mo
10mo
Nature Communications - LYMTACs are heterobifunctional small molecules that take advantage of lysosomal membrane proteins to degrade membrane targets via relocalization and lysosomal degradation,...
www.nature.com
Join us at Chemsymposia 2026 to discover groundbreaking research in physics applications. Connect with experts, engage in insightful discussions, and explore our venue, registration details, and speak...
Join Chemsymposia 2026: Research & Innovation | ChemSymposia 2026
LYMTACs:chimeric small molecules repurpose lysosomal membrane proteins for target protein relocalization and degradation
chemsymposia.com
Biology is governed by macromolecular interactions, perturbation of which often lies at the heart of disease. Most therapeutic drugs, whether they are small molecules or biologics, exert their effects...
www.science.org
Load and lock: An emerging class of therapeutics that influence macromolecular dissociation
Ryan Potts - real
Ryan Potts - real
Our latest paper w/ @pottslab.bsky.social & @amgen.bsky.social in @jacs.acspublications.org by co-first authors @cmzammit.bsky.social & Cory Nadel on discovery of covalent destabilizing degrader of AR & AR-V7 in prostate cancer. Thanks also to @themarkfdn.bsky.social ! pubs.acs.org/doi/10.1021/...
Jun 10, 2025
Mar 28, 2025
Now we’re finally talking! www.politico.com/news/2025/03...
What if treating disease meant stabilizing biology, not blocking it? We explore that idea in @ScienceMagazine with LOCKTAC molecular glues, a new class of molecules that stabilize natural interactions to either boost or block biology. science.org/doi/10.1126/sc…shorturl.at/976aj #mycompnay
🎓 Recent STEM grad? Jump-start your PhD journey with Amgen’s new 2-yr paid Postbaccalaureate Research Fellowship in Thousand Oaks! Work with world-class scientists, publish your findings, and make a real impact for patients. Apply by July 15 ➡️ amgen.wd1.myworkdayjobs.com/Careers/job/...
Carolyn Bertozzi
Carolyn Bertozzi
10mo
www.politico.com
Jun 14, 2025
Career Category Research Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients...
Postbaccalaureate Fellow - Research
science.org
amgen.wd1.myworkdayjobs.com
Ryan Potts - real
Ryan Potts - real
[email protected] @amgen.bsky.social demonstrate proof-of-concept of disease-specific targeted degradation by redirecting virally encoded E3 ubiquitin ligases with VIPER-TACs. http://dlvr.it/TJgF0r
Mar 21, 2025
10mo
Dan Nomura
A new #ScienceReview looks at a different approach to drug discovery that may enable drugging of unconventional targets through stabilization of macromolecular complexes with molecules known as “LOCKTACs.” Learn more: https://scim.ag/4lC2aCM
Cell Chemical Biology
Science Magazine