Delighted to share our latest paper out today - led by @ardeena-berisha.bsky.social - we show that we can boost the anti-cancer activity of human MAIT cells by getting them to use lactate & also directing them using bi-specific engagers as a proof of concept
academic.oup.com/jimmunol/art...
Abstract. Mucosal-associated invariant T (MAIT) cells are unconventional T cells, which upon activation can display potent cytotoxic and cytokine-producing