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Check out this exciting new report on NEDDylation of DNA polymerase eta. Happy our lab could contribute to this work led by @nicholaswashton.bsky.social and colleagues.
3mo
Irina Bezsonova
Pleased to share that our latest paper is out now in NAR. We demonstrate that Pol η binds to and is a substrate of NEDD8. @ncmoreno.bsky.social @txelah.bsky.social @barneslab.bsky.social @irinabezsonova.bsky.social academic.oup.com/nar/article/...
3mo
Abstract. DNA polymerase eta (Pol η) is a Y-family translesion polymerase responsible for synthesizing new DNA across UV-damaged templates. It is recruited
academic.oup.com
Human DNA polymerase η is regulated by mutually exclusive mono-ubiquitination and mono-NEDDylation
Nicholas William Ashton