Embryogenesis in 4D: a developmental atlas for genes and cells ๐งช
@schierlab.bsky.social developed a new method (#weMERFISH) that visualizes the activity of hundreds of genes across the entire zebrafish embryo with subcellular resolution.
lnkd.in/eHY5gXDx
@erc.europa.eu @snsf.ch @unibas.ch
With this โBehind the paperโ story, Iโd like to give special thanks to two remarkable contributors whose generosity made a big difference:
@jialinliu.bsky.social for the scMultiomics data behind the multiomic atlas,
and Guoqiang Yuโs group for sharing ITEC cell tracking, which enabled MERFISH-FATE.
Guoqiang Yuโs group developed ITEC, a powerful method for large-scale cell tracking and lineage reconstruction. Exciting new directions are demonstrated in our recent preprint: www.biorxiv.org/content/10.6...
A long-term collaboration finally coming together. Looking forward to seeing how people use it!
Very grateful to everyone who made this work possible. I feel incredibly lucky to have worked with such an amazing team.
Special thanks to: Jakob El Kholtei, KJ Jenie, @mcolomerr.bsky.social, and of course our wonderful collaborator Bogdan Bintu and my mentor @schierlab.bsky.social
Also huge thanks to @jialinliu.bsky.social, Qinghua Zhang, @mads100tist.bsky.social , Lucia Du, Mireia Codina Tobias, Mengfan Wang, Wei Zheng, Edward Lin, Serena Chuang, @mayseless.bsky.social , @hilsawh.bsky.social, Susan Mango, and Guoqiang Yu for making this work possible.
@jialinliu.bsky.social generated a time-resolved scMultiomics dataset that provides new insights into the regulatory logic of cell fate specification in early embryogenesis. Read the work here: www.biorxiv.org/content/10.1...
Excited to share that I will start my lab at the Center for Integrative Genomics in Lausanne @unil.bsky.social in Jan 2027! Iโm looking for PhD students fascinated by how cells build tissues and excited about developing new technologies to study development across scales. www.wanlab.bio/pages/9397
Join us 15 October to hear from two early-career researchers, @osvaldoics.bsky.social & Yinan Wan, working on development across scales.
Chaired by @dev-journal.bsky.social Executive Editor @amjeve.bsky.social.
๐ 15 October, 09:00 BST (UTC+1)
Register here: us02web.zoom.us/webinar/regi...