Listened to the talk by the first author at SfN and was pleasantly surprised to see so many synaptic proteins, including my all-time favorite: synaptojanin-1!
Nisha Rafiq
Whoa - neuronal ciliary proteome! Tons to dig into here - different from kidney cilia proteome (perhaps unsurprising) and enriched for many postsynaptic proteins, strengthening previous suggestions of cilia as postsynaptic signaling structures.
@nachury.bsky.social
www.biorxiv.org/content/10.1...
Neuronal cilia have emerged as crucial signaling hubs, yet their molecular composition and integration with synaptic communication remain poorly understood. Using a newly developed Arl13b-TurboID mous...