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JAMA Ophthalmology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications. 🌐 JAMAOphthalmology.com
JAMA Ophthalmology









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Swept-source #OCTA biomarkers, including choriocapillaris flow deficit and vessel skeleton density, distinguished normal cognition, MCI, and #AlzheimerDisease dementia, suggesting potential for noninvasive cognitive screening. ja.ma/43sRa48
Among three leading ophthalmology journals between mid-2024 and late 2025, STROBE guideline adherence was high for core reporting items but suboptimal for missing data, participant flow, and generalizability in recent ophthalmology observational studies. ja.ma/4dZGno4
📄 This case report discusses a diagnosis of central retinal artery occlusion with gradual reperfusion and improvement in the visual acuity after alprostadil treatment in a female patient aged 67 years. ja.ma/4eCllMs
In a patient with dome-shaped macula, acute hypotony after lens implantation led to complete resolution of chronic subretinal fluid sustained for >7 months, suggesting intraocular pressure modulation may influence fluid dynamics. ja.ma/4xfU0XO
Among patients with #diabetes in both SEED and UK Biobank cohorts, metformin use was not associated with reduced risk of age-related macular degeneration compared to other antidiabetic medication or no antidiabetic medication. ja.ma/4fum6rQ
📄 This case report discusses the finding of granular fluorescein flow on fluorescein angiography in a young boy with stage E retinoblastoma. ja.ma/4dUqE9W
In preterm infants undergoing retinopathy of prematurity screening, noncontact handheld optical coherence tomography caused less behavioral and physiological stress and fewer adverse events than contact fundus photography. ja.ma/4uLdKkv
Bedside optical coherence tomography imaging at 36 weeks' postmenstrual age in very preterm infants indicated RNFL thickness predicts motor and cognitive outcomes and lowers autism risk at age 2 years. ja.ma/4ocz6Vx
A smartphone-based #AI application enabled population-level self-screening for ocular surface malignancies, achieving specialist-level diagnostic accuracy and identifying rare tumors without enucleation. ja.ma/4x9lEpm
Six cases of postoperative fungal #Endophthalmitis after #CataractSurgery were linked to Sarocladium kiliense contamination in off-label trypan blue solution, emphasizing the need for sterilization and infection control. ja.ma/4aa31rl
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JAMA Ophthalmology