New online! Role of systemic and epicardial adipose tissue in cardiometabolic disease #CardioSky
Nature Reviews Cardiology, Published online: 16 June 2026; doi:10.1038/s41569-026-01304-9In this Review, Nerlekar and colleagues describe how the collective biology of adipose depots, rather than quantity alone, drives cardiometabolic risk, highlight how patterns of fat distribution specific to sex and ethnicity can modulate this risk, and summarize numerous pharmacological interventions to target adipose tissue for the reduction of cardiometabolic risk.
