Excited to share our latest work in collaboration with the @edreznik.bsky.social lab @mskcancercenter.bsky.social, where we describe functionally dominant mitochondrial DNA mutations in patient tumors. So, what is functional dominance in mitochondrial genetics, I hear you ask?
rdcu.be/eN1jm
Delighted to have been awarded the Hooke Medal. This recognition reflects not only my work, but the outstanding contributions of my group members over the years.👍
Our new study is out in Nature Communications.
Using TNBC organoid mouse models, we show that necroptosis in both tumour and stromal compartments cooperatively drives effective responses to immunogenic cell death–based immunotherapy.
🔗 www.nature.com/articles/s41...
Nature Genetics - Analysis of 14,106 tumor genomes highlights recurrent mutations in mitochondrial ribosomal RNA encoded within the mitochondrial genome. Mutations occur at hotspot positions and...
We are proud to support the 2nd Scottish Cell Biology Meeting on 4th September in Glasgow
Register now!
www.gla.ac.uk/events/confe...
Transitional Research Fellow (G8) (Ref 188913) - Closing Date 18th Jan 2026 - Come and join us! 🔬https://www.jobs.gla.ac.uk/job/transitional-research-fellow
🚨Excited to announce a new preprint from our lab, where we describe an ancient metabolic axis that controls mitochondrial genome copy number; a mechanism we uncovered in human cells that stretches through evolution to control mtDNA in flies, yeast and even plants!
Payam Gammage
It's shaping up to be an amazing line up at the Gordon Cell Death meeting! Register now! www.grc.org/cell-death-c...
There is still time to register for @focalplane.bsky.social's inaugural plant imaging webinar tomorrow. #plantimaging focalplane.biologists.com/2026/03/30/n...
Deadlines are approaching for @keystoneSymposia.bsky.social #InnateImmunity : Diversity in #HostDefense & Disease, this March in Banff! See key dates: keysym.us/KSInnateImmune26 #KSInnateImmune26
Call for papers: In Vitro Models of Human Disease to Inform Mechanism and Drug Discovery
Deadline approaching: Monday 3 November 2025
journals.biologists.com/dmm/pages/in...
#Biology #Research #Disease #Discovery #Organoids #Tumours #Gastruloids #Assembloids
Stephen Tait
Meier Lab ICR
School of Cancer Sciences
British Society for Cell Biology
Payam Gammage
Most advanced triple-negative breast cancers remain resistant to immunotherapy. Here, the authors discover that RIPK1-driven necroptosis in both tumor and stromal compartments is essential for effecti...
We are delighted to announce that @mitosrus.bsky.social from @cruk-si.bsky.social @glasgow.ac.uk has been awarded the 2026 Hooke Medal
You can read about Stephen's work on mitochondria, cell death and cancer here:
bscb.org/hooke-medal-...
Inflammasome Lab
Inflammasome Lab
The Company of Biologists
The Company of Biologists
www.biorxiv.org
British Society for Cell Biology
Job Purpose We have an exciting opportunity for an experienced Research Fellow to make a leading contribution to cancer research and related fields working with PIs within the School of Cancer Sci...
