Using live cell single particle tracking, we studied real time dynamics between TRiC chaperonin system and its substrates in the crowded cellular environment. Take a pook!
Nature research paper: Single-molecule dynamics of the TRiC chaperonin system in vivo
go.nature.com/4qZM3Cn
go.nature.com
Single-particle tracking experiments in intact cells reveal dynamic co- and post-translational interactions of the TRiC–PFD chaperonin complex with client proteins during in vivo protein folding.
