Using live cell single particle tracking, we studied real time dynamics between TRiC chaperonin system and its substrates in the crowded cellular environment. Take a pook!
I'm thrilled to share our new publication, with co-first author @ Niko Dalheimer, is now out on Nature. Check out how we use live cell single particle tracking to study real time dynamics between TRiC chaperonin system and it substrates in the crowded cellular environment.
"Single-molecule dynamics of the #TRiC #chaperonin system in vivo" is out @nature.com.
❕Publication: www.nature.com/articles/s41...
❕Press Release: www.biochem.mpg.de/live-broadca...
Authors: @rongqinxiaoxiao.bsky.social, @niko-dalheimer.bsky.social, @mamueller.bsky.social, F.-Ulrich Hartl
Max Planck Institute of Biochemistry
Nature research paper: Single-molecule dynamics of the TRiC chaperonin system in vivo
go.nature.com/4qZM3Cn
Single-particle tracking experiments in intact cells reveal dynamic co- and post-translational interactions of the TRiC–PFD chaperonin complex with client proteins during in vivo protein folding.
I’m excited to share my first-author paper, with co-first author @rongqinxiaoxiao.bsky.social, now out in @nature.com. We developed a live-cell single-particle tracking platform to see how TRiC & prefoldin engage proteins during co- and post-translational folding. 1/9 www.nature.com/articles/s41...
Single-particle tracking experiments in intact cells reveal dynamic co- and post-translational interactions of the TRiC–PFD chaperonin complex with client proteins during in vivo protein folding.
