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If leading AI companies are indeed approaching the point of recursive self-improvement, a coordinated, verifiable, and universally applied pause is probably the only responsible solution to mitigate several major AI risks; at least until safety guarantees are developed and demonstrated. (1/2)
10d
Yoshua Bengio
Tracking the 3D motion of loop anchors in multiple genomic regions, we confirm that TADs are highly dynamic. Our analyses indicate that TADs constantly fold into multiple extruding loops that bring anchors briefly together ~1x per hour, effectively shrinking their genomic distance by ~0.1 kb/s.(2/4)