Breen is right that "we truly have no idea."
Also, this sprawling conversation is not limited to the humanities + CS. Sociologists have been very active. See Kozlowski et al. "In Silico Sociology" — and many critiques of "silicon sampling" — and this interesting theoretical piece by Skarpelis:
Ted Underwood
📖 New publication out 📖
This piece is a first attempt at articulating why computational social science needs qualitative and historical approaches—especially as we begin to rely more heavily on simulation.
sociologica.unibo.it/article/view...