All currently approved antibiotics inhibit essential cellular processes. Ever wonder if we could kill bacteria using the opposite strategy?
Here, we demonstrate an alternative antibacterial strategy: lethality through pathway over-activation.
www.nature.com/articles/s41...
(1 out of 3)
Here, the authors report metabolic activation as a potential antimicrobial strategy against Mycobacterium tuberculosis. They show that supra-physiological activation of L-histidine biosynthesis r...
