🧠 Pairing bursectomy with thymus removal revealed the split that defines immunology: B cells (bursa-derived, antibodies) and T cells (thymus-derived, cellular immunity).
The "B" in B cell stands for bursa.
🐔 Then an accident. Fellow student Timothy Chang borrowed Glick's birds for an antibody demo against Salmonella.
80% failed to make antibodies, all of them the bursectomized ones. Glick had stumbled onto the organ responsible for antibody production.
📊 Everything builds on it. Monoclonal antibodies (a multi-billion-dollar drug class), CAR-T cancer therapy, vaccine design, bone marrow transplants, AIDS research.
Glick: 225 papers, 29 students trained, NIH/NSF/USDA funded, Golden Goose Award 2018.
🔬 Science rejected the paper. It ran in Poultry Science, ignored for years.
Then pediatrician Max Cooper used it to crack why some immunodeficient children mounted only partial immune responses.
Neuroscientist here, who has talked about the US losing science ground to other countries:
The biggest problem for generating future cures for brain diseases is the ongoing utter destruction of US basic neuroscience.
It’s not about regulation.
🧪 Every vaccine, every antibody drug, every immune-deficiency diagnosis traces to a gland nobody understood in a chicken's posterior.
This is what foundational research looks like before anyone knows what it's for.
More 👇
bioniclab.substack.com/notes
#YourTaxDollarsAtWork #BasicResearch #NIH #NSF
China’s beating the US in neuroscience:
“There is a very real possibility that without significant regulatory reform, if you’re a wealthy American, in 10 years, the only place you’ll be able to get your state-of-the-art cancer care is in Shanghai,” said Max Hodak, former president of Neuralink.
TK (Takashi DY) Kozai
TK (Takashi DY) Kozai
TK (Takashi DY) Kozai
TK (Takashi DY) Kozai
TK (Takashi DY) Kozai
TK (Takashi DY) Kozai
“This is going to be one of the three or four major plot lines of the next decade,” former Neuralink president says.
