🎉Kicking off 2026 with our first paper from the Freudenthal lab in NAR. Ribonucleotides reshape telomeric G4s and are resistant to RNase H2 repair. Congrats to the authors and huge thanks to our collaborator Hui-Ting Lee! academic.oup.com/nar/article/...
Abstract. Human telomeres are composed of TTAGGG repeats that can fold into G-quadruplexes (G4s). G4s can form several different conformations, including p
