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We were especially happy to see our UGA-42 Caliburn used. Targeted ablation helped probe how E-cadherin-directed actin–spectrin networks shape cortical mechanics.
👏Congratulations to Soffer et al. and all authors on this excellent work.
Full paper:
rupress.org/jcb/article/...
Soffer et al. identify spectrin as a central component of epithelial cortical actomyosin networks to control cortex mechanics and signaling. Changes in the