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RAPP OptoElectronic
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☀️ June is here, and conference season is in full swing.
We are excited to be joining the #EESMechanobiology in #EMBLHeidelberg and connecting with the #mechanobiology community.
👏 Thank you to the scientific organizers, @embo.org, @embl.org, and @events.embl.org for bringing this symposium together.
🎉 Congratulations to all authors on this brilliant paper and the well-deserved JCB cover feature!
👏 A beautiful study connecting cortical cytoskeleton organization, cell shape, signaling, and epidermal differentiation. We are truly excited to see our technology contribute to this outstanding work.
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⚡ A pulsed UV laser with high peak power can induce localized lesions with subnuclear precision.
⚙️ UGA-42 Caliburn is designed for this type of controlled, localized laser damage: moving a small focused pulsed laser spot within the FOV for precise #photomanipulation workflows.
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✨ We are truly delighted to be a Gold Sponsor of #ELMI2026.
🤝 We are also especially pleased to share a booth with our good friends from Chroma Technology Corp. and TOPTICA Photonics as we rely on strong collaborations and trusted, long-term partnerships.
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We were especially happy to see our UGA-42 Caliburn used. Targeted ablation helped probe how E-cadherin-directed actin–spectrin networks shape cortical mechanics.
👏Congratulations to Soffer et al. and all authors on this excellent work.
Full paper:
rupress.org/jcb/article/...
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Sven @swarnck.bsky.social, Simona, and Konstantinos will be there to reconnect with old friends, meet new colleagues, and discuss #bioimaging, #photomanipulation, and advanced #microscopy workflows.
👏Huge thanks to @ppbioimaging.bsky.social for the incredible organization. See you in Coimbra!
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How does the cortical #cytoskeleton connect cell shape w/ cell fate?
A recent @jcb.org @rupress.org paper by Soffer et al. uses the #epidermis to study how shape transitions are coordinated w/ differentiation.
The study identifies #spectrin as an essential organizer of the #actomyosin cortex.
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Layer-specific cortical organization helps integrate mechanics, signaling, and epidermal barrier formation.
The work was also featured on the cover of the JCB issue.
We made a short summary of the key findings, but the full paper contains many more experiments worth reading.
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🧬 For #DNArepair studies, chemically-induced damage is often too blunt.
🎯 Local laser-induced #DNAdamage changes the experimental game. Instead of damaging the whole sample, one can target a selected nuclear region and follow the response over time with #LiveImaging.
#Microscopy #Bioimaging
🔬 The #EMBO | #EMBL Symposium "Mechanobiology across the tree of life" is well underway here in Heidelberg.
💡 Come by our booth to talk about #photomanipulation, laser ablation, #FLUCS, and custom microscopy solutions for #mechanobiology experiments.
👋 See you at the booth!
#EESMechanobiology
