Genome Plasticity and Computational Genetics.
We develop cutting-edge technologies to explore genome evolution!
Lab Website: https://schneebergerlab.org/
Schneeberger Lab
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For the R3a/b locus, we found striking evidence for at least two distinct haplotypes circulating in European breeding 🔍 We also generated a draft genome assembly of S. demissum 'El Desierto', confirming a single sub-genome origin of the introgression.
We extended the MCA framework to SNP data 🧬 Using a 20K SNP array, we identified post-1945 introgressed haplotypes and traced their spread through the pedigree. Two introgressions now occur in ~half of all European varieties!
We first curated a pedigree database of 12,041 potato varieties 📚 and identified the Major Contributing Ancestors (MCAs) of 1,209 European varieties. Top contributors: Katahdin 🇺🇸, Saskia 🇳🇱, and Agria 🇩🇪, present in the ancestry of the majority of modern European potato!
The European potato germplasm traces back to just a few founding genotypes 🌱
Since then, introgressions from wild relatives have reshaped the gene pool. However, how these haplotypes spread through breeding lineages has remained largely unresolved.
These two high-frequency introgressions trace back to S. tuberosum Group Andigena clone CPC 1673 (H1 nematode resistance, Chr5) and S. demissum (R3a/b late blight resistance, Chr11) - both entering the gene pool through multiple independent lineages.
🥔 We traced the ancestral legacy of modern breeding introgressions in European potato! Combining pedigree records & genome-wide SNPs, we reveal which wild relatives shaped the European gene pool and how.
📄 doi.org/10.1007/s00122-025-05143-z
🌾 We have an open postdoc position in Plant Genomics in our group at HHU Düsseldorf!
If you enjoy computational biology, asking big questions, and the satisfaction of code working on the first try, check out schneebergerlab.org/career/
Apply by Mar. 31 | 3-year postdoc | German skills required
