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Revision of @sarahpugly.bsky.social's ๐Ÿชฐ walking CPG preprint: www.biorxiv.org/content/10.1... Major updates: โ†’ motor rhythms replicate across 4 connectomes (incl. 2 new full-CNS datasets) โ†’ robust across all 6 legs โ†’ new analyses of the CPG motif show it's an outlier in the VNC โ†’ improved code docs
1mo
John Tuthill
for the cpg curious, we made this video to explain the project www.youtube.com/watch?v=twAZ...
New preprint: Whole-body 3D kinematics of freely behaving ๐ท๐‘Ÿ๐‘œ๐‘ ๐‘œ๐‘โ„Ž๐‘–๐‘™๐‘Ž New tech from @blobology.bsky.social & others at @hhmijanelia.bsky.social, which @ispizua.bsky.social and @elliottabe.bsky.social used to gain insight into 3D structure of locomotion & courtship www.biorxiv.org/content/10.6...
1mo
1mo
Video
John Tuthill
YouTube video by Bing Wen Brunton
www.youtube.com
Connectome simulations identify a central pattern generator circuit for fly walking
John Tuthill
Cool new work from @dudman.bsky.social and @fluketc.bsky.social Reward magnitude determines reinforcement learning efficiency: www.science.org/doi/10.1126/...
Mindscape 352 | Bing Brunton @bingbrunton.bsky.social on Connecting the Connectome to the Body. #MindscapePodcast www.preposterousuniverse.com/podcast/2026...
1mo
22d
Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...
www.science.org
Reward magnitude determines reinforcement learning efficiency
I got to nerd out with @seanmcarroll.bsky.social last week ๐Ÿ˜Ž
We tracked mice in space! This video shows our estimate of their self-induced centripetal force during circling in 3D ๐Ÿ‘ฉโ€๐Ÿš€ Preprint thread below ๐Ÿ‘‡
Run, donโ€™t walk, to your closest local preprint server to see our latest 3D tracking results! Iโ€™m still tickled that our results show flies donโ€™t exactly walk, they โ€œground runโ€ everywhere. I bet they also talk fast and suffer no fools.
1mo
1mo
1mo
A new preprint shows that deep learning can make a fly walk realistically using a wormโ€™s brain โ€” exposing a fundamental problem with how connectome models are being built and sold to investors. By @natmesanash.bsky.social #neuroskyence www.thetransmitter.org/systems-neur...
2mo
Researchers have long searched for the neural circuit underlying locomotion. Now theyโ€™ve found it in flies. By @natmesanash.bsky.social #neuroskyence www.thetransmitter.org/systems-neur...
Video
Jibran Khokhar
Sean Carroll
1mo
The sphinx, with a wormโ€™s brain and a flyโ€™s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
www.thetransmitter.org
โ€˜Digital sphinxโ€™ raises questions about connectome models
Mindscape 352 | Bing Brunton @bingbrunton.bsky.social on Connecting the Connectome to the Body. #MindscapePodcast www.preposterousuniverse.com/podcast/2026...
New preprint: Whole-body 3D kinematics of freely behaving ๐ท๐‘Ÿ๐‘œ๐‘ ๐‘œ๐‘โ„Ž๐‘–๐‘™๐‘Ž New tech from @blobology.bsky.social & others at @hhmijanelia.bsky.social, which @ispizua.bsky.social and @elliottabe.bsky.social used to gain insight into 3D structure of locomotion & courtship www.biorxiv.org/content/10.6...
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
www.thetransmitter.org
Long-sought walking circuit found in fruit flies
Bing Wen Brunton
Bing Wen Brunton
1mo
Talmo Pereira
1mo
Video
The Transmitter
The Transmitter
Sean Carroll
John Tuthill
1/ New preprint! ๐ŸงชWith @talmo.bsky.social and team, we used deep learning on archival NASA video of mice on the ISS. Turns out mice in microgravity become tiny acrobats: huddling to sleep, doing backflips, even briefly generating their own ~1g. #SpaceBiology #OpenScience #NASA #SLEAP
1mo
www.biorxiv.org
Amelia Eisch ๐Ÿงช๐Ÿง ๐Ÿ‘ฉโ€๐Ÿ”ฌ ๐Ÿ