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We have written up a tutorial on how to run BindCraft, how to prepare your input PDB, how to select hotspots, and various other tips and tricks to get the most out of binder design! github.com/martinpacesa...
Barcoded viral tracing identifies immunosuppressive astrocyte–glioma interactions @quintanalabhms.bsky.social @nature.com www.nature.com/articles/s41...
A triumph of perseverance from twitterless Tom Weber, Christine Biben and the team, our in vivo barcoding "LoxCode mouse" used to resolve epiblast fate to fetal organs is finally published in @cellpress.bsky.social and available through @jacksonlab.bsky.social www.sciencedirect.com/science/arti...
@saramostafavi.bsky.social (@Genentech) & I (@Stanford) r excited to announce co-advised postdoc positions for candidates with deep expertise in ML for bio (especially sequence to function models, causal perturbational models & single cell models). See details below. Pls RT 1/
If post doc opportunities in ML for genomics were a mountain, then perched at the summit, straddling the border between impossibly alluring and actually real, sits this. You. Should. Apply.
Introducing Arc Institute’s first virtual cell model: STATE
🧑‍🔬📰🚀 #RxivMaker is here! A framework automating the creation of publication-ready scientific #preprints from simple Markdown. Goodbye manual formatting, and hello gorgeous manuscripts! A great adventure with @guijacquemet.bsky.social's lab 📜: zenodo.org/records/1575... 👨‍💻: github.com/HenriquesLab...
Join the @steinaerts.bsky.social Lab via the VIB.AI International PhD Call 2025! Use ML to decode how DNA sequences control gene activity. Work with single-cell & spatial genomics, deep learning models, and CRISPR validation. 📍 Leuven 🗓️ Apply by June 22nd → https://tinyurl.com/53nc9vnd
11mo
FutureHouse's goal has been to automate scientific discovery. Now we used our agents to make a genuine discovery – a potential new treatment for one kind of blindness (dAMD). We had multiple cycles of hypotheses, experiments, and data analysis – including identify the mechanism.
Jun 25, 2025
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Much remains to be learned about the clonal fate of mammalian epiblast cells. Here, we develop high-diversity Cre recombinase-driven LoxCode barcoding…
www.sciencedirect.com
LoxCode in vivo barcoding reveals epiblast clonal fate bias to fetal organs
Martin Pacesa
Waggoner Lab
Anshul Kundaje
Shalin H. Naik
Arc Institute
Lee Zamparo
Ricardo Henriques
VIB.AI
Andrew White 🐦‍⬛
@saramostafavi.bsky.social (@Genentech) & I (@Stanford) r excited to announce co-advised postdoc positions for candidates with deep expertise in ML for bio (especially sequence to function models, causal perturbational models & single cell models). See details below. Pls RT 1/
Jun 19, 2025
Anshul Kundaje