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The timeline of co-transcriptional #mRNA processing and #modification may have to be revised: cleavage, termination, and #m6A deposition may occur earlier than most #splicing! Potential textbook changing study in bioRxiv by edueyras.bsky.social & Rippei Hayashi labs! www.biorxiv.org/content/10.1...
Apr 29, 2025
mRNA synthesis requires extensive pre-mRNA maturation, the organisation of which remains unclear. Here, we directly sequence pre-mRNA without metabolic labelling or amplification to resolve transcript...
www.biorxiv.org
Single-molecule multimodal timing of in vivo mRNA synthesis
Fascinating role of astrocytes uncovered.
The deadline for the @cshlmeetings course on #autism spectrum disorder is approaching. This was my entry into the field more than 15 years ago. While this will be my final year co-organizing it, I am looking forward to the stimulating discussions in the beautiful Banbury Center. More details 👇
Apr 17, 2025
May 16, 2025
Hello, fellow Cell & Developmental Biology enthusiasts! Check out our fresh-off-the-oven program for the 2025 Cell & Developmental Biology Symposium at NSW! #ANZSCDB #CellBiology #DevelopmentalBiology Please submit your abstract, and join us on Nov 5th, 2025!
Postdoc opening in my lab, joint with Prof Lee-Hwa Tai, to develop genomics, transcriptomcis and immunology pipelines for cancer immunotherapy. Details here or DM me: mqvlab.com/positions/
I am recruiting a postdoc with experience in Protein Biochemistry, Structural Biology & Chromatin Biology. If you are passionate about the complex world of chromatin modifications, please contact me for more details 🙏. Location: SAiGENCI, Adelaide, Australia 🦘🍷🏄🏖️🇦🇺
8mo
Feb 4, 2025
Dec 10, 2024
Apr 9, 2025
Apr 13, 2025
BBB-crossing lipid nanoparticles to deliver mRNA to neurons and astrocytes, published at @naturematerials.bsky.social
Super excited our paper on circRNA stability in the brain and their use as life experience markers is out! @inespatop.bsky.social www.cell.com/cell-reports...