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New from the lab: Fatty Acid Metabolism Sets the Species-specific Tempo of Cortical Development through Protein Acetylation Dynamics. Led by amazing trio: @ryo2iwata.bsky.social , Isabel Gallego, @emirerkol.bsky.social, together with @steinaerts.bsky.social , @fendtlab.bsky.social
📢 🚨 Technical Assistant Opportunity in Neuroscience 📢 🚨 Join us at @lmumuenchen.bsky.social and support research on how neural circuits 🧠 drive adaptive behavior! ⏳ Deadline: 15. November 2025 Learn more and apply: www.fens.org/careers/job-...
From RNA to evolution: Come join our next keynote lecture on the choreography of brain development by @debbysilver.bsky.social, Professor at Duke University! 📍September 15 at 11am in NQ105 in Martinsried Art by @somedonkey.bsky.social
Thrilled to share that our work is now published in Science! ✨ We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! 🧭 www.science.org/doi/10.1126/... 🧵1/
9mo
Only a few weeks left to apply for our 4-year PhD position, using human brain organoids & multi-omic methods to study genes implicated in speech disorders. Application deadline 5 Jan 2026. Fellowship is embedded in the International Max Planck Research School. More info: www.mpi.nl/imprs-phd-fe...
Ventral telencephalic progenitor maturation is gated by developmental timing, revealing a distinct regulatory logic underlying the development of inhibitory neurons @annrosebright.bsky.social @flo-neuhaus.bsky.social aus.bsky.social, @chr-mayer.bsky.social www.nature.com/articles/s41...
New from the Bocchi Lab in Nature Communications: Cortical astrocytes arise from two distinct progenitor lineages with specialized roles. Glad my lab could support the lineage tracing part using TrackerSeq. Congratulations to @bocchiric.bsky.social and the whole team! www.nature.com/articles/s41...
Interested in developmental epigenetics? So are we! Apply now to join us for your postdoc! Multiple positions across multiple groups @mrc-lms.bsky.social Projects spanning germline demethylation, gene regulation, genome architecture in development & disease 👇👇 lms.mrc.ac.uk/work/vacanci...
8mo
9mo
9mo
Developmental processes display temporal differences across species, leading to divergence in organ size and composition. In the cerebral cortex, neurons of diverse identities are generated sequential...
www.biorxiv.org
6mo
11mo
Species-specific Rates of Fatty Acid Metabolism Set the Scale of Temporal Patterning of Corticogenesis through Protein Acetylation Dynamics
10mo
New preprint from our lab on bioRxiv: “Stoichiometric transcription factor partnerships control GABAergic neuron fate allocation” www.biorxiv.org/content/10.6... A great collaboration with @annrosebright.bsky.social, Connor Lynch, @chr-mayer.bsky.social, and many others.
11mo
Unlike cortical progenitors, ventral telencephalic progenitors retain the ability to generate diverse neuron types during neurogenesis. Here, the authors show that ventral telencephalic progenitor mat...
www.nature.com
Pierre Vanderhaeghen
Temporal control of progenitor competence shapes maturation in GABAergic neuron development in mice - Nature Neuroscience
8d
Applications are now open for up to five postdoctoral positions in the area of developmental epigenetics.
lms.mrc.ac.uk
MRC Postdoctoral Research Scientists x 5 - MRC Laboratory of Medical Sciences
Astrocytes display diverse molecular and functional features in the brain, but the developmental origins of this heterogeneity are not well understood. Here, the authors show that two separate progeni...
www.nature.com
Dual lineage origins contribute to neocortical astrocyte diversity - Nature Communications
Combinatorial transcription factor (TF) codes specify neuronal fates, yet how quantitative differences in interacting TFs shape these decisions remains unresolved. We address this in the developing ba...
www.biorxiv.org
Stoichiometric transcription factor partnerships control GABAergic neuron fate allocation
Emilie Macé
Anna Schroeder
Nature Neuroscience
MPI for Biological Intelligence
Christian Mayer
Simon Fisher
Vicki Metzis
Elena Dvoretskova
🚨 First paper from the Bocchi lab out now in @natcomms.nature.com! We show that astrocytes in the cortex arise from not one, but two distinct progenitor lineages, each giving rise to specialized subtypes with distinct roles. Here the story📖 doi.org/10.1038/s414...
10mo
Dual lineage origins contribute to neocortical astrocyte diversity - Nature Communications
Astrocytes display diverse molecular and functional features in the brain, but the developmental origins of this heterogeneity are not well understood. Here, the authors show that two separate progeni...
doi.org
Riccardo Bocchi