How do you ensure the stability of a platform with millions of data points updated every release? You start testing patterns
In the last release of the Open Targets Platform, we implemented automated end-to-end testing into our development workflow 🧬🖥️
blog.opentargets.org/end-to-end-t...
blog.opentargets.org
As a platform grows in complexity, maintaining stability becomes increasingly difficult. The Open Targets Frontend Team has introduced automated end-to-end testing to ensure that core user journeys an...
In particular, they found an upregulation of MHC-I driven by interferon, which persists in progenitor cells after visible inflammation heals. They also point to ITGA4+ macrophages as key drivers of inflammation, acting through JAK/STAT signalling and cytokine expression.
This work, part of a broader ‘IBDverse’ project in the Anderson lab, was a collaboration between Open Targets, the @sangerinstitute.bsky.social, and @cuh.nhs.uk
Congratulations to the team!
“Open Targets has had the single biggest impact in integrating the @sangerinstitute.bsky.social and @ebi.embl.org science, above and beyond any other initiative I’ve seen in that time." 🤝