🧬Want to synthesise kilobase-scale DNA? We got you covered!🥳 In latest from the lab we explore the "doodling" capabilities of DNA polymerases and ways to guide the sequences produced. Loads of data + beautiful AFM of the molecules themselves. #synbio ... doi.org/10.1038/s414...
New on @biorxiv!!!!!!
We’re excited to share our latest paper on combining cell-free systems and machine learning to express full genome in vitro.
Check it out now! 👉 www.biorxiv.org/content/10.1...
Catch us at SEED in Houston this June to discuss this work.
#CellFree
Analysis and control of untemplated DNA polymerase activity for guided synthesis of kilobase-scale DNA sequences
doi.org/10.1038/s414...
New scientific publication by the group of Thomas Gorochowski on DNA synthesis
Thomas Gorochowski
Olivier Borkowski
🤖📚🧪#AI is having such a big impact on #synbio and science more broadly. Check out our latest perspective "Knowledge preservation in the era of big science and AI" on this topic that emerged from a workshop led by Penn Rainford a year or so ago! doi.org/10.1038/s414...
Science routinely discards valuable knowledge, from unpublished negative results to the tacit expertise lost when researchers move on. Here, the authors propose a roadmap for preserving this hidden kn...doi.org
🧬Want to synthesise kilobase-scale DNA? We got you covered!🥳 In latest from the lab we explore the "doodling" capabilities of DNA polymerases and ways to guide the sequences produced. Loads of data + beautiful AFM of the molecules themselves. #synbio ... doi.org/10.1038/s414...
Work emerged from discussions with the wonderfully creative @adrianwoolfson.bsky.social and Andrew Hessel, with Sim and Thea doing the heavy lifting in the lab. Would love to build a team to take this towards programmable DNA printers and I'm sure doodling plays an interesting role in evolution!
A fun (and mostly coherent!) discussion with Ezra Chapman on the intersection of AI and engineering biology. We live in such exciting times and I hope some of that excitement came across. Thanks Ezra for the invite. #engbio #synbio #ai
www.youtube.com/watch?v=SC4X...
Hey, if anyone wants to support my SpliceCraft project, where proceeds go to paying for Claude Code Max, I set up a Ko-Fi account. No pressure, of course. This project is born free and will remain free forever. TYIA! 💚
ko-fi.com/atinygreencell
Many microorganisms modify their movement in response to light. This new #JRSocInterface paper has developed an integrated pipeline capable of acquiring temporal imaging data and extracting kinematics to create digital twins: doi.org/10.1098/rsif... @chofski.bsky.social
