Our new paper showing two new doxycycline mechanisms against the ribosome has been accepted at Nature comms! 👌 The early access version is available here: www.nature.com/articles/s41... @daumlab.bsky.social @the-gold-lab.bsky.social @lsiexeter.bsky.social @exeter.ac.uk
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The common antibiotic doxycycline inhibits the ribosome. Here, using cryo-EM, the authors identify additional binding sites for doxycycline in the Coxiella burnetii and E. coli ribosomes.