Newest paper up on bioRxiv!
www.biorxiv.org/content/10.1...
Our new paper showing two new doxycycline mechanisms against the ribosome has been accepted at Nature comms! 👌 The early access version is available here: www.nature.com/articles/s41... @daumlab.bsky.social @the-gold-lab.bsky.social @lsiexeter.bsky.social @exeter.ac.uk
Early Christmas present! @mathewmclaren.bsky.social @willstuart.bsky.social @daumlab.bsky.social
The common antibiotic doxycycline inhibits the ribosome. Here, using cryo-EM, the authors identify additional binding sites for doxycycline in the Coxiella burnetii and E. coli ribosomes.www.nature.com
Cryo-EM reveals multiple mechanisms of ribosome inhibition by doxycycline www.biorxiv.org/content/10.1101/2025.11.08.686982v1 #cryoEM
The Gold Lab
Check out our structure of the archaeal virus HFTV1! Amazing work by two students - Daniel Zhang and Becky Davies, supported by @mathewmclaren.bsky.social. Great collaboration with T. Quax & S. Schwarzer, @hanna-m-oksanen.bsky.social, @the-gold-lab.bsky.social, @misha-isupov.bsky.social & W. Stuart.
Here is a shoutout to @quaxlab.bsky.social, who is an amazing collaborator on this project and just joined BlueSky. 🦠🔬Wellcome Tessa! #ArchaeaSky
@archaeabiotech.bsky.social
The preprint is published here! www.biorxiv.org/content/10.1....
Welcome new scope! 🔬 ❄️
cryoEM papers
cryoEM papers
The Daum Lab
The Daum Lab
The Daum Lab
The Daum Lab
Antimicrobial resistance is driving the search for new antibiotics and a greater understanding of their mechanism of action. Doxycycline is amongst the most-prescribed antimicrobials. It demonstrates ...
