2025 off to a decent start...Happy to share my latest first author paper with the brilliant Nela Fialova and @axelmontagne.bsky.social where we sought to identify genes that are frequently altered in vascular cells in CNS disorders across existing datasets. Check it out here!
Michael Sewell
🚨 Latest contribution where we delve into the dementia-related snRNAseq data & spotlight the signature changes in #endothelialcells and #pericytes!
Proud of the effort led by Dr. Michael Sewell @pichaelmichael.bsky.social and Nela Fialova.
alz-journals.onlinelibrary.wiley.com/doi/full/10....
INTRODUCTION Cerebrovascular dysfunction plays a critical role in the pathogenesis of dementia and related neurodegenerative disorders. Recent omics-driven research has revealed associations between...