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Homologous recombination (HR) deficiency upon Breast Cancer Gene 2 (BRCA2) loss arises from defects in the formation of RAD51 nucleoprotein filaments. We demonstrate that loss of the anti-recombinase ...
www.science.org
FIGNL1 inhibits homologous recombination in BRCA2 deficient cells by dissociating RAD51 filaments
